After doing some tweaking in Reshade i found a preset which makes the colours in Tower pop out a bit more.
Reshade Off
Reshade On
Also a Before and After Gif
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first one looks better IMO
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Yeah i still need to tweak it some more. Reshade is pretty neat for altering the look of games.
Neat! Just a little too saturated for my taste, but good work. 
Too much contrast you got there budd
Reshade is only really good if you want to do cinematic screenshots, I tried using reshade on some games, and honestly no matter how much you configure it, there’s always either too much or too little of something.